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risk-of-bias

@astoreyai/ai_scientist
2
0

Assess risk of bias in research studies for systematic reviews. Use when: (1) Conducting systematic reviews, (2) Evaluating study quality, (3) GRADE assessments, (4) Meta-analysis planning.

Install Skill

1Download skill
2Enable skills in Claude

Open claude.ai/settings/capabilities and find the "Skills" section

3Upload to Claude

Click "Upload skill" and select the downloaded ZIP file

Note: Please verify skill by going through its instructions before using it.

SKILL.md

name risk-of-bias
description Assess risk of bias in research studies for systematic reviews. Use when: (1) Conducting systematic reviews, (2) Evaluating study quality, (3) GRADE assessments, (4) Meta-analysis planning.
allowed-tools Read, Write
version 1.0.0

Risk of Bias Assessment Skill

Purpose

Systematically evaluate methodological quality and potential biases in research studies.

Tools by Study Design

RCTs: Cochrane Risk of Bias 2 (RoB 2) Non-randomized: ROBINS-I Diagnostic Studies: QUADAS-2 Prognostic Studies: QUIPS

RoB 2 Domains

  1. Randomization Process

    • Adequate sequence generation?
    • Allocation concealment?

  2. Deviations from Interventions

    • Blinding effective?
    • Adherence to protocol?

  3. Missing Outcome Data

    • Complete data?
    • Appropriate handling?

  4. Outcome Measurement

    • Blinded assessment?
    • Validated measures?

  5. Selective Reporting

    • All outcomes reported?
    • Pre-registered?

Risk Levels

  • Low: Minimal bias
  • Some concerns: Potential bias
  • High: Serious bias likely

Integration

Use with literature-reviewer agent for systematic quality assessment of included studies.

Version: 1.0.0